-isysroot does not take multiple architectures into account
When multiple architectures are set in CMAKE_OSX_ARCHITECTURES, e.g. "arm64;armv7;x86_64", the -isysroot flag can't be passed unconditionally, as the SDK in the single CMAKE_OSX_SYSROOT may not support all the architectures. This is typically the case of iOS simulator and device SDKs.
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