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When both VTK and ITK are built with the same CMAKE_RUNTIME_OUTPUT_DIRECTORY settings, the H5detect and H5make_libsettings programs are generated by both VTK and ITK. These are intended to be internal build configuration programs that determine the capabilities of the local compiler and OS. When VTK and ITK diverge in their version of HDF5, conficts occur that cause difficult to debug compiler errors. By adding a prefix here the program name conflict can be avoided.
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