{
  "Scenario": {
    "Name": "AlbuterolValidation",
    "Description": "Patient using Albuterol with an inhaler.",
  "PatientConfiguration": { "PatientFile": "StandardMale.json" },
    "DataRequestManager": {
      "SamplesPerSecond": 1.0,
      "DataRequest": [{
        "DecimalFormat": {
          "Precision": 9
        },
        "Category": "LiquidCompartment",
        "CompartmentName": "VenaCava",
        "SubstanceName": "Albuterol",
        "PropertyName": "Concentration",
        "Unit": "ug/mL"
      }, {
        "DecimalFormat": {
          "Precision": 6
        },
        "Category": "Substance",
        "SubstanceName": "Albuterol",
        "PropertyName": "PlasmaConcentration",
        "Unit": "ug/L"
      }, {
        "DecimalFormat": {
          "Precision": 2
        },
        "Category": "Substance",
        "SubstanceName": "Albuterol",
        "PropertyName": "SystemicMassCleared",
        "Unit": "ug"
      }, {
        "DecimalFormat": {
          "Precision": 2
        },
        "Category": "Substance",
        "SubstanceName": "Albuterol",
        "PropertyName": "MassInBody",
        "Unit": "ug"
      }, {
        "DecimalFormat": {
          "Precision": 4
        },
        "Category": "Substance",
        "CompartmentName": "LeftKidneyTissue",
        "SubstanceName": "Albuterol",
        "PropertyName": "PartitionCoefficient"
      }, {
        "DecimalFormat": {
          "Precision": 4
        },
        "Category": "Substance",
        "CompartmentName": "RightKidneyTissue",
        "SubstanceName": "Albuterol",
        "PropertyName": "PartitionCoefficient"
      }, {
        "DecimalFormat": {
          "Precision": 4
        },
        "Category": "Substance",
        "CompartmentName": "BrainTissue",
        "SubstanceName": "Albuterol",
        "PropertyName": "PartitionCoefficient"
      }, {
        "DecimalFormat": {
          "Precision": 4
        },
        "Category": "Substance",
        "CompartmentName": "RightLungTissue",
        "SubstanceName": "Albuterol",
        "PropertyName": "PartitionCoefficient"
      }, {
        "DecimalFormat": {
          "Precision": 4
        },
        "Category": "Substance",
        "CompartmentName": "LeftLungTissue",
        "SubstanceName": "Albuterol",
        "PropertyName": "PartitionCoefficient"
      }, {
        "DecimalFormat": {
          "Precision": 4
        },
        "Category": "Substance",
        "CompartmentName": "LiverTissue",
        "SubstanceName": "Albuterol",
        "PropertyName": "PartitionCoefficient"
      }, {
        "DecimalFormat": {
          "Precision": 4
        },
        "Category": "Substance",
        "CompartmentName": "BoneTissue",
        "SubstanceName": "Albuterol",
        "PropertyName": "PartitionCoefficient"
      }, {
        "DecimalFormat": {
          "Precision": 4
        },
        "Category": "Substance",
        "CompartmentName": "FatTissue",
        "SubstanceName": "Albuterol",
        "PropertyName": "PartitionCoefficient"
      }, {
        "DecimalFormat": {
          "Precision": 4
        },
        "Category": "Substance",
        "CompartmentName": "SkinTissue",
        "SubstanceName": "Albuterol",
        "PropertyName": "PartitionCoefficient"
      }, {
        "DecimalFormat": {
          "Precision": 4
        },
        "Category": "Substance",
        "CompartmentName": "MuscleTissue",
        "SubstanceName": "Albuterol",
        "PropertyName": "PartitionCoefficient"
      }, {
        "DecimalFormat": {
          "Precision": 4
        },
        "Category": "Substance",
        "CompartmentName": "SpleenTissue",
        "SubstanceName": "Albuterol",
        "PropertyName": "PartitionCoefficient"
      }, {
        "DecimalFormat": {
          "Precision": 4
        },
        "Category": "Substance",
        "CompartmentName": "GutTissue",
        "SubstanceName": "Albuterol",
        "PropertyName": "PartitionCoefficient"
      }, {
        "DecimalFormat": {
          "Precision": 4
        },
        "Category": "Substance",
        "CompartmentName": "MyocardiumTissue",
        "SubstanceName": "Albuterol",
        "PropertyName": "PartitionCoefficient"
      }, {
        "DecimalFormat": {
          "Precision": 2
        },
        "Category": "LiquidCompartment",
        "CompartmentName": "LiverTissueIntracellular",
        "SubstanceName": "Albuterol",
        "PropertyName": "MassCleared",
        "Unit": "ug"
      }, {
        "DecimalFormat": {
          "Precision": 2
        },
        "Category": "LiquidCompartment",
        "CompartmentName": "LeftKidneyTissueIntracellular",
        "SubstanceName": "Albuterol",
        "PropertyName": "MassCleared",
        "Unit": "ug"
      }, {
        "DecimalFormat": {
          "Precision": 2
        },
        "Category": "LiquidCompartment",
        "CompartmentName": "RightKidneyTissueIntracellular",
        "SubstanceName": "Albuterol",
        "PropertyName": "MassCleared",
        "Unit": "ug"
      }, {
        "DecimalFormat": {
          "Precision": 2
        },
        "Category": "LiquidCompartment",
        "CompartmentName": "LeftKidneyTissueIntracellular",
        "SubstanceName": "Albuterol",
        "PropertyName": "MassExcreted",
        "Unit": "ug"
      }, {
        "DecimalFormat": {
          "Precision": 2
        },
        "Category": "LiquidCompartment",
        "CompartmentName": "RightKidneyTissueIntracellular",
        "SubstanceName": "Albuterol",
        "PropertyName": "MassExcreted",
        "Unit": "ug"
      }, {
        "DecimalFormat": {
          "Precision": 2
        },
        "Category": "LiquidCompartment",
        "CompartmentName": "LiverTissueIntracellular",
        "SubstanceName": "Albuterol",
        "PropertyName": "MassExcreted",
        "Unit": "ug"
      }]
    },
    "AnyAction": [{
      "AdvanceTime": {
        "Time": {
          "ScalarTime": {
            "Value": 30.0,
            "Unit": "s"
          }
        }
      }
    }, {
      "EquipmentAction": {
        "InhalerConfiguration": {
          "Configuration": {
            "Substance": "Albuterol",
            "MeteredDose": {
              "ScalarMass": {
                "Value": 90.0,
                "Unit": "ug"
              }
            },
            "NozzleLoss": {
              "Scalar0To1": {
                "Value": 0.04
              }
            },
            "SpacerVolume": {
              "ScalarVolume": {
                "Value": 500.0,
                "Unit": "mL"
              }
            }
          }
        }
      }
    }, {
    "PatientAction": {
      "ConsciousRespiration": {
        "Command": [{
          "ForcedExhale": {
            "ExpiratoryReserveVolumeFraction": {
              "Scalar0To1": {
                "Value": 1.0
              }
            },
            "ExhalePeriod": {
              "ScalarTime": {
                "Value": 3.0,
                "Unit": "s"
              }
            }
          }
        }, {
          "UseInhaler": {
          }
        }, {
          "ForcedInhale": {
            "InspiratoryCapacityFraction": {
              "Scalar0To1": {
                "Value": 1.0
              }
            },
            "InhalePeriod": {
              "ScalarTime": {
                "Value": 12.0,
                "Unit": "s"
              }
            },
            "HoldPeriod": {
              "ScalarTime": {
                "Value": 3.0,
                "Unit": "s"
              }
            },
            "ReleasePeriod": {
              "ScalarTime": {
                "Value": 5.0,
                "Unit": "s"
              }
            }
          }
        }]
      }
    }
  }, {
      "AdvanceTime": {
        "Time": {
          "ScalarTime": {
            "Value": 720.0,
            "Unit": "min"
          }
        }
      }
    }]
  },
  "Configuration": {
    "DrugsConfiguration": {
      "PDModel": "Off"
    }
  }
}