diff --git a/Source/cmVisualStudio10TargetGenerator.cxx b/Source/cmVisualStudio10TargetGenerator.cxx
index cc1586d220704ad8684ae6b58c652bca5df52e57..ba0cf9ca4de48546a1f3281c71f810e45ba26160 100644
--- a/Source/cmVisualStudio10TargetGenerator.cxx
+++ b/Source/cmVisualStudio10TargetGenerator.cxx
@@ -2277,6 +2277,20 @@ void cmVisualStudio10TargetGenerator::WriteAllSources(Elem& e0)
                           std::back_inserter(exclude_configs));
 
       Elem e2(e1, tool);
+      bool isCSharp = (si.Source->GetLanguage() == "CSharp");
+      if (isCSharp && exclude_configs.size() > 0) {
+        std::stringstream conditions;
+        bool firstConditionSet{ false };
+        for (const auto& ci : include_configs) {
+          if (firstConditionSet) {
+            conditions << " Or ";
+          }
+          conditions << "('$(Configuration)|$(Platform)'=='" +
+              this->Configurations[ci] + "|" + this->Platform + "')";
+          firstConditionSet = true;
+        }
+        e2.Attribute("Condition", conditions.str());
+      }
       this->WriteSource(e2, si.Source);
 
       bool useNativeUnityBuild = false;
@@ -2321,7 +2335,7 @@ void cmVisualStudio10TargetGenerator::WriteAllSources(Elem& e0)
       if (si.Source->GetPropertyAsBool("SKIP_PRECOMPILE_HEADERS")) {
         e2.Element("PrecompiledHeader", "NotUsing");
       }
-      if (!exclude_configs.empty()) {
+      if (!isCSharp && !exclude_configs.empty()) {
         this->WriteExcludeFromBuild(e2, exclude_configs);
       }
     }
diff --git a/Tests/CSharpOnly/CMakeLists.txt b/Tests/CSharpOnly/CMakeLists.txt
index 195af05cb4f9fc2358b5313c2f478854d13f330a..f7928b675f9562a8dcee10a4aaed9f0be6a75e95 100644
--- a/Tests/CSharpOnly/CMakeLists.txt
+++ b/Tests/CSharpOnly/CMakeLists.txt
@@ -9,8 +9,13 @@ source_group(nested FILES nested/lib1.cs)
 add_library(lib2 SHARED lib2.cs)
 
 add_executable(CSharpOnly csharponly.cs)
-
 target_link_libraries(CSharpOnly lib1 lib2)
 
+add_executable(CSharpConfigSpecific
+  $<$<CONFIG:Debug>:config_specific_main_debug.cs>
+  $<$<NOT:$<CONFIG:Debug>>:config_specific_main_not_debug.cs>
+  $<$<CONFIG:NotAConfig>:config_specific_main_no_exist.cs>
+  )
+
 add_custom_target(CSharpCustom ALL SOURCES empty.cs)
 add_custom_target(custom.cs ALL DEPENDS empty.txt)
diff --git a/Tests/CSharpOnly/config_specific_main_debug.cs b/Tests/CSharpOnly/config_specific_main_debug.cs
new file mode 100644
index 0000000000000000000000000000000000000000..b62524b74b33607beb2b3043de0c9c833419549b
--- /dev/null
+++ b/Tests/CSharpOnly/config_specific_main_debug.cs
@@ -0,0 +1,10 @@
+namespace CSharpConfigSpecific
+{
+    class CSharpConfigSpecific
+    {
+        public static void Main(string[] args)
+        {
+            return;
+        }
+    }
+}
diff --git a/Tests/CSharpOnly/config_specific_main_no_exist.cs b/Tests/CSharpOnly/config_specific_main_no_exist.cs
new file mode 100644
index 0000000000000000000000000000000000000000..b62524b74b33607beb2b3043de0c9c833419549b
--- /dev/null
+++ b/Tests/CSharpOnly/config_specific_main_no_exist.cs
@@ -0,0 +1,10 @@
+namespace CSharpConfigSpecific
+{
+    class CSharpConfigSpecific
+    {
+        public static void Main(string[] args)
+        {
+            return;
+        }
+    }
+}
diff --git a/Tests/CSharpOnly/config_specific_main_not_debug.cs b/Tests/CSharpOnly/config_specific_main_not_debug.cs
new file mode 100644
index 0000000000000000000000000000000000000000..b62524b74b33607beb2b3043de0c9c833419549b
--- /dev/null
+++ b/Tests/CSharpOnly/config_specific_main_not_debug.cs
@@ -0,0 +1,10 @@
+namespace CSharpConfigSpecific
+{
+    class CSharpConfigSpecific
+    {
+        public static void Main(string[] args)
+        {
+            return;
+        }
+    }
+}